Generate report on the number of HPO disease modifiers

[bschilder]

• [x] Severity modifier
• [x] Lazarin Tiers (manual annotations from Momoko)
• [x] Lazarin Tiers (auto)
• [x] age of onset
• [x] age of death
• [x] phenotype frequency
• [x] Evidence
• [x] Aspect
• [x] Reference
• [x] Biocuration
• [x] Qualifier
• [x] Sex
• [x] disease database source
• [x] additional modifiers

[bschilder]

Full report here:

https://neurogenomics.github.io/RareDiseasePrioritisation/reports/HPO_annotations

[bschilder]

@NathanSkene requested the following:

phenotypes with 20+ diseases’s with associated meta-data

[NathanSkene]

What I meant was a bit more detailed than that. Meant what we discussed on the call the other day:

Can we say, that this phenotype, when it acts via this celltype, has a different clinical course?

• To answer this, we want to have at least one phenotype, that has 20 diseases associated with it, where they have at least two different clinical course values (each with >10 diseases)

[bschilder]

Got it, will write a separate report for this.

[bschilder]

Made a new issue for this here: #23