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neurorestore / Libra

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Differential expression on genes detected in min number of cells #16

Open sshakil12 opened 2 years ago

sshakil12 commented 2 years ago

Hello,

Does libra have the same capability as Seurat to only test genes that are detected in a minimum fraction of min.pct cells in either of the two populations when performing differential expression. In other words, does it have a similar min.pct argument as Suerat's FindAllMArkers() function?

Best, S.

jordansquair commented 2 years ago

We didn't implement this since you typically want the DE information on every gene. You would need to subset that before run_de.