nextstrain / dengue

Nextstrain build for dengue virus
https://nextstrain.org/dengue
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Add E gene builds #17

Closed j23414 closed 3 months ago

j23414 commented 8 months ago

Context

By user request:

Is there any chance we could get a E gene build of nextstrain dengue? Much more sequences of E than full genome, especially in some parts of the world

Description

Examples

Possible steps to a solution

  1. Pull out E gene sequence from the dengue reference.gb file to be used as the reference for the E gene builds. a. Or follow rsv rules
  2. Add a filter_length_per_group function for “all_E”, “denv1_E”, “denv2_E”, etc similar to filter_sequences_per_group.
  3. Add E to the dropdown under “Dataset” by appending _E and _genome (e.g. dengue_denv1_genome.json and dengue_denv1_E.json and updating the nextstrain.org manifest file.

Dependencies

joverlee521 commented 8 months ago

For posterity, the workflow changes are on the phylogenetic_dir_E branch.

j23414 commented 5 months ago

Explore adding {gene}_coverage metadata columns for any gene/locus of interest using Nextclade, taking inspiration from the following RSV script:

ammaraziz commented 5 months ago

I'm that annoying user. Thank you so much for the E tree, it's been super helpful.

j23414 commented 4 months ago

Instead of documenting progress in individual PRs, e.g.

Posting the latest plan for the E gene workflow pipeline (so far) here:

pathogen-repo-guide (7)

j23414 commented 3 months ago

Closed as completed since the following PRs are merged: