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nf-cmgg / germline

A nextflow pipeline for calling and annotating small germline variants from short DNA reads for WES and WGS data
https://nf-cmgg.github.io/germline/
MIT License
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Explore `VariantRecalibrator` and `ApplyVQSR` for better filtering #166

Open nvnieuwk opened 5 months ago

nvnieuwk commented 5 months ago

Description of feature

https://gatk.broadinstitute.org/hc/en-us/articles/360036510892-VariantRecalibrator https://gatk.broadinstitute.org/hc/en-us/articles/360037056912-ApplyVQSR

=> Also look at Sarek

matthdsm commented 5 months ago

Noooooo, tooo slooooowww There's a reason bcbio didn't do it

nvnieuwk commented 5 months ago

I should have made the title a bit clear :grin: