nf-core / differentialabundance

Differential abundance analysis for feature/ observation matrices from platforms such as RNA-seq
https://nf-co.re/differentialabundance
MIT License
64 stars 37 forks source link

Create 'differential' subworkflow #341

Open pinin4fjords opened 2 weeks ago

pinin4fjords commented 2 weeks ago

Description of feature

There work ongoing at https://github.com/nf-core/differentialabundance/pull/288 to support a benchmarking/ multi-paramset use case. But I think more work needs to be done on the components.

A first easy win is a differential workflow to bundle DESeq2, Limma, and (in future) other differential methods into one subworkflow, along with post-filtering operations etc. Changing the currently released workflow logic to use that will provide an easier basis to work from.

pinin4fjords commented 2 weeks ago

nf-core/modules component in progress at https://github.com/nf-core/modules/pull/6951