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nhanhocu / metamicrobiomeR

An R package for analysis of microbiome relative abundance data using zero inflated beta GAMLSS and meta-analysis across microbiome studies using random effects models
https://github.com/nhanhocu/metamicrobiomeR
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Meta analysis for single group? #20

Closed valery-shap closed 1 year ago

valery-shap commented 1 year ago

Hello, Thank you for the useful package! I have a question about appropriate data for it. All the examples are about comparing two groups that are preset in each paper. But I have a bit different task. For example, I have 10 papers with the data(mean relative abundance) of one group and 20 papers with the data for another group. And I’d like to compare them. Could I use the package for this type of analysis?

Best regards, Valery

nhanhocu commented 1 year ago

Hi, Sorry for late reply. I guess the package is not designed for the task you mentioned in term of meta-analysis. However, if only for comparison between two groups using GAMLSS, you can try pooling data from all studies and do the comparison. Bests, Nhan

valery-shap commented 1 year ago

Hello, thank you for reply! do you mean that one package: https://www.gamlss.com/? Could you advice the function for this goal? Best regards, Valery