nhejazi / biotmle

:package: :microscope: R/biotmle: Targeted Learning with Moderated Statistics for Biomarker Discovery
https://code.nimahejazi.org/biotmle/
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interpretation of ATE "fold change" #25

Closed nhejazi closed 6 years ago

nhejazi commented 7 years ago

"Fold change" is a misleading term for the output generated by the biomarker TMLE procedure. While consistent with terminology employed by the limma package (and in the bioinformatics literature in general), the results produced by the procedure are more similar to a log-risk difference (really, a log-ATE) rather than a fold change (~log-OR)...