"Fold change" is a misleading term for the output generated by the biomarker TMLE procedure. While consistent with terminology employed by the limma package (and in the bioinformatics literature in general), the results produced by the procedure are more similar to a log-risk difference (really, a log-ATE) rather than a fold change (~log-OR)...
"Fold change" is a misleading term for the output generated by the biomarker TMLE procedure. While consistent with terminology employed by the
limma
package (and in the bioinformatics literature in general), the results produced by the procedure are more similar to a log-risk difference (really, a log-ATE) rather than a fold change (~log-OR)...