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nickjcroucher / gubbins

Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins
http://nickjcroucher.github.io/gubbins/
GNU General Public License v2.0
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Description of extensive-search mode? #343

Closed nicolettacommins closed 12 months ago

nicolettacommins commented 2 years ago

I'm not able to find in the manual a description of what is happening in the extensive-search mode? Could the developers provide a quick explanation about what exactly is different compared to the default mode? Thanks!

nickjcroucher commented 2 years ago

It's a small change to the search strategy for recombinations - by default, Gubbins will use a threshold number of SNPs to identify recombinations. This used to sometimes be higher than the minimum number of SNPs in a recombination; that's now been changed, such that the threshold starts at the previous default, but is then decreased (the new default behaviour), or the threshold starts as the minimum number of SNPs (with the --extensive-search flag). I don't think the --extensive-search makes a big difference on most bacterial datasets. I'll add this to the manual.