nipy / mindboggle

Automated anatomical brain label/shape analysis software (+ website)
http://mindboggle.info
Other
145 stars 54 forks source link

Mean curvature values very different from FreeSurfer's #40

Closed binarybottle closed 10 years ago

binarybottle commented 10 years ago

Mindboggle mean curvature values are all negative while FreeSurfer values are all positive, and with very different absolute values (ex: subject OASIS-TRT-20-1). Travel depth values are above 1 but all geodesic depth values are between 0 and 1. I'll need help figuring these things out.

curvature() is run here: https://github.com/binarybottle/mindboggle/blob/master/mindboggle/mindboggle#L776 which calls this: https://github.com/binarybottle/mindboggle/blob/master/mindboggle/shapes/shape_tools.py#L111 which in turn calls CurvatureMain.

The curvature values are written to a table here: https://github.com/binarybottle/mindboggle/blob/master/mindboggle/utils/io_table.py#L389

binarybottle commented 10 years ago

Joachim Giard's response (@joachimgiard):

The mean curvature is a measure of the convergence of the normal vector. For a sphere, it is negative everywhere, unless you consider the normal vector are pointing inside. It is logical that a topological sphere has a negative average mean curvature. It is a matter of scale choice.

The values are subject to the same kind of choices. The mean curvature is inversely proportional to the radius of circles you are able to fit on the surfaces. So, for a symmetrical hole (both principal curvatures are the same), an absolute value of 5 means you can fit a sphere of radius 0.2. Since meshes are discrete surfaces, in theory, the curvature is 0 on polygons and infinite on edges and vertices. It is thus necessary to take the average in a neighborhood.

A solution to compare curvatures may be to normalize them before computing the average per region. In our case, the curvature for the cuneus has a high value for both our measure and the fs curvature. Is it a region with fewer sulci?

binarybottle commented 10 years ago

Some of the regions with higher curvature in fs are higher in mb, and likewise for low curvature, but there are clear exceptions, such as pericalcarine and transverse temporal. I wonder why there should be such discrepancies? (the cuneus has lots of folding: http://en.wikipedia.org/wiki/Cuneus)

joachimgiard commented 10 years ago

I think, again, that the estimation choices may lead to such differences. It could be good to take a look at the curvature (without averaging) on a complete surface and to have a closer look to those particular regions.