Scaling seems to be off when there is only one parameter being estimated

nlmixr2 / nlmixr2est

nlmixr2 estimation routines

https://nlmixr2.github.io/nlmixr2est/

GNU General Public License v2.0

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Closed mattfidler closed 1 month ago

mattfidler commented 1 month ago

Also one parameter being estimated is a special case problem that has specialized optimization algorithms, these should be selected instead.

mattfidler commented 1 month ago

[x] Review existing optimization algorithms in the project to identify those that can handle the special case of estimating a single parameter effectively.
[x] Implement or integrate the identified specialized optimization algorithms.
[x] Test the new implementation to ensure it resolves the scaling issue.