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nlmixrdevelopment / nlmixr

nlmixr: an R package for population PKPD modeling
https://nlmixrdevelopment.github.io/nlmixr/
GNU General Public License v2.0
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mrgsolve and nlmixr #48

Closed KyleBarrett closed 6 years ago

KyleBarrett commented 6 years ago

I have been attempting to write the ODE's and model inputs using mrgsolve while using nlmixr for parameter estimation, similar to this link: https://github.com/metrumresearchgroup/mrgsolve/issues/307

However, Im working with a two-compartment ODE-based model and prefer to use saem over nlme. Saem() requires the ODE's be in RxODE format, so I think it would be easier to use nlmixr(est="saem") as it allows additional model classes to be used. I was wondering if you had any examples similar to the above link, but using the saem method instead.

mattfidler commented 6 years ago

We have a PBPK and semi-mechanistic model example that we plan to share after the PAGE meeting. I think those would qualify, but will be shared in ~2 weeks.

KyleBarrett commented 6 years ago

Hi Matt, I think that would clarify some of my questions as well. Looking forward to their release!

mattfidler commented 6 years ago

A draft is availble here:

https://github.com/nlmixrdevelopment/PAGE-2018

It may change the location, if so I will update the url for you.