nlmixrdevelopment / nlmixr

nlmixr: an R package for population PKPD modeling
https://nlmixrdevelopment.github.io/nlmixr/
GNU General Public License v2.0
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Steady state data modeling #529

Closed ghost closed 3 years ago

ghost commented 3 years ago

Hello, I went through the examples posted on https://nlmixrdevelopment.github.io/nlmixr/articles/modelPiping.html but I could not figure out how to handle data that represent steady state PK. Is there a way to model steady state data?

Thanks

mattfidler commented 3 years ago

Hi @melagha ,

nlmxir uses the data to figure out if there is steady state. Since nlmixr uses the RxODE simulation engine it handles this in the same way as RxODE.

Here is a link that describes steady state handling in nlmixr and RxODE:

https://nlmixrdevelopment.github.io/RxODE/articles/RxODE-event-types.html#steady-state-1

ghost commented 3 years ago

Awesome. Appreciate your prompt response.