Open jranke opened 2 years ago
Thank you for reporting this. We found a few memory issues that we have fixed and will be pushing in the new rxode2
/nlmixr2
. Unfortunately, windows is the most difficult platform to track down an issue like this.
OK, thanks for the feedback! nlmixr2 looks promising, so I will have a look. From the github README it really seems to be ready to use, can you give me a hint on the status?
On second thought, this really sounds like I should abandon my nlmixr backend for mkin, as I do not see how I could be able to push it to CRAN... Would you recommend that I switch to nlmixr2 already and wait with a CRAN release of the nlmixr(2) backend for nlmixr2 to be released to CRAN?
I am hoping to release soon, as always it is up to you. I need to move vignettes around and put some assertions in as well as track down any bugs.
From a function point of view the code should be the same between nlmixr
and nlmixr2
in most cases. The controls will be slightly different (ie foceiControl()
, saemControl()
, and nlmixControl()
/nlmixrNlmeControl()
have been aligned and now check to make sure that the right types of values are supplied.
Also, it seems that nlme
performs a little worse for the theo_sd
dataset. For me, I am unsure if it is because of a rewritten nlme
engine (I could have changed residual weights for normal/additive error)
Since you are not calling the foceiControl
and saemControl
but using nlmixr_model
it should work in both versions.
OK, thanks a lot for your feedback!
When I run the first example in the nlmixr help page:
My R session consistently crashes when using R-devel (r81847 ucrt) under Windows. The crash occurs after a couple of minutes on my system. When I turn off buffered output, I can see that the crash occurs after the message "calculating Jacobian".
I came across this problem trying to find out why my test setup script crashes Winbuilder for R-devel and rhub/r-devel-windows.