nlmixrdevelopment / nlmixr

nlmixr: an R package for population PKPD modeling
https://nlmixrdevelopment.github.io/nlmixr/
GNU General Public License v2.0
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Vitamins #641

Closed charos529 closed 1 year ago

charos529 commented 1 year ago

Hello . Has smn developed PK models for vitamins with long half-life . I have population average data .I tried to use NCA to estimate parameters and then used nls function . But I am getting negative clearence and very big Ka .