better approximate mageck with median instead of mean

noamteyssier / crispr_screen

Efficient Differential Expression and Gene Aggregation for CRISPR screens.

https://noamteyssier.github.io/crispr_screen/

MIT License

6 stars 0 forks source link

Closed noamteyssier closed 1 year ago

noamteyssier commented 1 year ago

for replicate numbers >2 mageck uses the median of normalized counts to approximate sgRNA counts while I am currently using the mean.