nopara73 / LongevityWorldCup

https://www.longevityworldcup.com/
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Which Biological Clock to use? #9

Closed nopara73 closed 1 month ago

nopara73 commented 1 month ago

The biological clock may change every year. Since every year a new LWC starts. It's probably important to use a clock that shows biological age instead of pace of aging. This gives an edge to older athletes and larger age reversals are rewarded accordingly.

nopara73 commented 1 month ago

It'd be good if we could get an order of magnitude improvement on user experience of taking the test on existing competitions. Otherwise market demand may conflict. However compromising on science too much also not very appealing.

For example pheno age requires a traditional blood test instead of a home testing kit. Is that even more user friendly? In some ways it's better, but in some ways it's worse. Here are some other ideas.

Here are some ideas to make biological age testing dramatically easier:

1. Smartphone-Based Facial Analysis

How It Works: Utilize advanced AI algorithms to analyze facial features using a smartphone camera. The software assesses skin texture, wrinkles, facial morphology, and other visual biomarkers that correlate with aging.

Advantages:

Non-Invasive: No physical contact or samples required.

Instant Results: Immediate feedback after image capture.

Accessibility: Available to anyone with a smartphone.

2. Voice Biomarker Analysis

How It Works: Analyze voice recordings to detect biomarkers associated with aging. Changes in voice pitch, tone, and speech patterns can reflect physiological aging processes.

Advantages:

Ease of Use: Simply speak into a microphone or smartphone.

Remote Participation: Can be done from anywhere without special equipment.

Quick Assessment: Results generated rapidly.

3. Wearable Device Data

How It Works: Leverage data from wearables like smartwatches or fitness trackers. Metrics such as heart rate variability, sleep patterns, and activity levels are analyzed to estimate biological age.

Advantages:

Continuous Monitoring: Provides a more comprehensive view over time.

Passive Data Collection: Minimal user effort required.

Personalized Insights: Data can be tailored to individual baselines.

4. Online Lifestyle Questionnaire

How It Works: Use scientifically validated questionnaires that assess diet, exercise, stress levels, sleep quality, and other lifestyle factors known to influence biological aging.

Advantages:

No Physical Samples Needed: Completely non-invasive.

Immediate Results: Automated scoring systems provide quick feedback.

Broad Accessibility: Can reach a wide audience regardless of technology access.

5. Photoplethysmography (PPG) via Smartphone

How It Works: Measure blood flow and heart rate variability by having users place their fingertip over the smartphone camera and flash. PPG signals can provide insights into vascular health and biological aging.

Advantages:

Simple Process: Users follow straightforward instructions.

No Additional Devices: Utilizes existing smartphone hardware.

Quick Analysis: Data can be processed in real-time.

6. Saliva-Based Epigenetic Testing

How It Works: Instead of blood samples, use saliva to analyze DNA methylation patterns associated with aging.

Advantages:

Less Invasive: Easier and more comfortable sample collection.

Simplified Shipping: Saliva samples are easier to store and mail.

Accurate Biomarkers: Epigenetic markers provide precise biological age estimates.

7. Physical Function Self-Assessments

How It Works: Users perform simple physical tests at home—such as grip strength, balance tests, or sit-to-stand exercises—and input their results into an app.

Advantages:

No Special Equipment: Uses household items or bodyweight.

Functional Insights: Directly measures aspects of physical aging.

Engaging Experience: Encourages users to participate actively.

8. Skin Autofluorescence via Smartphone

How It Works: Use the smartphone camera with a specialized app to measure skin autofluorescence, which correlates with the accumulation of advanced glycation end-products (AGEs) linked to aging.

Advantages:

Non-Invasive: Simple scan of the skin surface.

Convenient: Can be performed anytime, anywhere.

Educational: Increases awareness of factors affecting skin health.

9. Eye Age Estimation

How It Works: Analyze images of the retina or iris using a smartphone attachment to assess vascular and neural indicators of aging.

Advantages:

Detailed Biomarkers: Eyes can reveal systemic health conditions.

Non-Invasive: Quick image capture without discomfort.

Innovative: Leverages cutting-edge research linking ocular features to aging.

10. Gamified Cognitive Tests

How It Works: Offer engaging, game-like cognitive tests that assess memory, reaction time, and problem-solving abilities, which can decline with age.

Advantages:

Fun and Engaging: Encourages participation through interactive content.

Accessible: Can be deployed via web platforms or mobile apps.

Immediate Feedback: Users receive scores upon completion.

nopara73 commented 1 month ago

Maybe it's best to do 2025 with PhenoAge because this is the only year income is not yet expected from test sells and PhenoAge is based on traditional blood tests which leaves no room for test sells and therefore won't have the opportunity to hqve PhenoAge later

nopara73 commented 1 month ago

PhenoAge it is