nservant / HiC-Pro

HiC-Pro: An optimized and flexible pipeline for Hi-C data processing
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m #345

Closed BenxiaHu closed 3 years ago

nservant commented 4 years ago

Hi, Do you have the same if you start from raw data ? The iced normalization usually removes low counts rows/columns. The threshold can be changed in the config. But as cooler is able to normalize on the fly the data, I usually advice to convert the raw data into cool file. N