nservant / HiC-Pro

HiC-Pro: An optimized and flexible pipeline for Hi-C data processing
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mHi-C vs. HiC-Pro RM_MULTI = 0 #551

Open pna059 opened 1 year ago

pna059 commented 1 year ago

Hi, I have a genome where regular mapping of data yields 60% multimapped reads. At first, I dealt with that by using HiC-Pro with the RM_MULTI = 0 option. Thank I discovered the special tool mHiC https://github.com/yezhengSTAT/mHiC. Have you ever compared the outcomes for the two options? Thanks!