nservant / HiC-Pro

HiC-Pro: An optimized and flexible pipeline for Hi-C data processing
Other
386 stars 182 forks source link

Polyploidy #630

Closed Rhia15 closed 6 months ago

Rhia15 commented 7 months ago

Hi there, I am working on a few hexaploid genome assemblies and wanted to try this tool for providing the inputs for EndHiC. I was wondering if this would be able to handle high ploidy levels? I have now ran HiC-pro over night and it is still making the bam files in bwt2_global and they're around 4G each currently, is it normal to take this long in just making these files or should I stop it?

Thank you!

nservant commented 6 months ago

Hi, I do not see any reason why the running time would be correlated with the ploidy of the data. Just let it run ;)