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Cures, successful treatments outcomes #35

Open GoogleCodeExporter opened 8 years ago

GoogleCodeExporter commented 8 years ago 
We need terms that describe getting better. For instance how to describe a 
process in which a 
disorder is reduced or eliminated?

Original issue reported on code.google.com by alanruttenberg@gmail.com on 30 Oct 2009 at 2:04

GoogleCodeExporter commented 8 years ago

Original comment by alanruttenberg@gmail.com on 30 Oct 2009 at 2:06

GoogleCodeExporter commented 8 years ago 
Barry's response 

'Cure', off the top of my head, is the name for a process-type that has been 
regularly applied successfully 
to create process instances, which can be designated as instances of this type 
only retrospectively. ('To 
cure' is like 'to win', 'to convince'.)

The corresponding non-success verb is, I think, to treat -- it is thus the term 
'treatment', I think, that 
should be added to OGMS

'Outcome' I think should be included (this can of course also be negative)

We need a term for the process of getting better -- any suggestions?

Original comment by alanruttenberg@gmail.com on 1 Nov 2009 at 5:49

GoogleCodeExporter commented 8 years ago 
Terms associated with decrease of amount of a disorder:

clearing (eg of an infection)
remission (of cancer and other cases)

Original comment by alanruttenberg@gmail.com on 1 Nov 2009 at 5:51

GoogleCodeExporter commented 8 years ago 
Another possible term is 'convalescence' (the connotation is a gradual 
progression of
getting better)

Original comment by albertgo...@gmail.com on 1 Dec 2009 at 2:15

GoogleCodeExporter commented 8 years ago 
Added 'treatment' (OGMS:0000090) and 'convalescence' (OGMS:0000091) in OGMS 
v0.5

Original comment by albertgo...@gmail.com on 31 Mar 2010 at 4:28

GoogleCodeExporter commented 8 years ago 
Could treatment be renamed "disorder treatment" for example? OBI just started
discussing treatment as part of investigations - in this case there is no 
intent to
cure, and it includes drug testing, chemical administration etc.

Original comment by mcour...@gmail.com on 31 Mar 2010 at 5:05

GoogleCodeExporter commented 8 years ago 
Lots of treatments aren't technically intended to cure.  We know that insulin
administration, pharmaceutical management of hypertension and asthma, etc, etc 
all do
not cure.

And of course, OGMS definition of treatment thereby does not mention cure at 
all.

I do not think phase I trials involve a treatment.

Would like to know more about your use cases and proposed definitions of 
'treatment'
in OBI, though.

Original comment by hoga...@gmail.com on 31 Mar 2010 at 5:16

GoogleCodeExporter commented 8 years ago 
Current definitions is "A processual entity whose completion is hypothesized 
(by a
healthcare provider) to alleviate the signs and symptoms associated with a 
disorder".

I was suggesting the label update to disambiguate between (from
http://en.wikipedia.org/wiki/Treatment)
1. A type of therapy used to remedy a health problem
2. Experimental treatment, the levels of treatment factor(s) (variables 
controlled by
the experimenter) applied

I think 1. is what OGMS aims at covering, while 2. would be in the scope of OBI.

Original comment by mcour...@gmail.com on 1 Apr 2010 at 6:16

GoogleCodeExporter commented 8 years ago 
I don't understand definition #2, at least partly because it's circular 
(defining
treatment in terms of 'treatment').

You don't know whether something is a treatment or not until after an experiment
demonstrates efficacy.  Seems odd to call it a 'treatment' before then.

Original comment by hoga...@gmail.com on 2 Apr 2010 at 2:52