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"pathological formation" and "pathological anatomical structure"? #58

Open GoogleCodeExporter opened 8 years ago

GoogleCodeExporter commented 8 years ago 
What is the difference between "pathological formation" and "pathological 
anatomical structure"?

These should be given a textual definition asap

Original issue reported on code.google.com by MBrochhausen@gmail.com on 12 Dec 2010 at 11:46

GoogleCodeExporter commented 8 years ago 
It is also unclear exactly what the difference between ‘pathological 
anatomical structure’ and ‘disorder’ is.  At the very least, it is 
unclear why they are sister classes instead of disorder being the parent of 
pathological anatomical structure.

Here are the current definitions:

'disorder' is defined as: "A material entity which is clinically abnormal and 
part of an extended organism. Disorders are the physical basis of disease."

'pathological anatomical structure' is defined as: "An anatomical structure 
(FMA) is pathological whenever (1) it has come into being as a result of 
changes in some pre-existing canonical anatomical structure, (2) through 
processes other than the expression of the normal complement of genes of an 
organism of the given type, and (3) is predisposed to have health-related 
consequences for the organism in question manifested by symptoms and signs."

'pathological structure' does not have a definition at this time.

Original comment by Alexande...@gmail.com on 13 Jun 2012 at 6:30