disease phenotype

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Peter Robinson says:
>8)  Disease Phenotype =def. A clinical phenotype that is
>characteristic of a single disease.
>==>> This raises the question of how a disease is defined? Is there
>one disease per disorder? What if two disorders cause
>indistinguishable diseases (e.g.,
><http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=209900)>http://www.ncbi.nlm
.nih.gov/entrez/dispomim.cgi?id=209900).
>In any case, this needs to be stated more clearly.

Original issue reported on code.google.com by albertgo...@gmail.com on 27 Jul 2009 at 3:44

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There is nothing in any of the definitions that restricts diseases to one 
disorder,
or disorders to one disease.  If two disorders cause the same disease, and that
disease has a "disease phenotype", then so be it: two disorders result in the 
same
disease phenotype, or rather, one disease phenotype may have any one of several
disorders as the physical basis of its underlying disease.  I see no problem 
for the
definition of disease phenotype.

Original comment by hoga...@gmail.com on 2 Aug 2009 at 11:10

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Original comment by albertgo...@gmail.com on 1 Dec 2009 at 6:15

• Changed state: WontFix