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The Ontology for Biomedical Investigations
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Adding a term for MCC-Seq #756

Closed obi-bot closed 7 years ago

obi-bot commented 9 years ago

Hello, I'd like to request a new ontology term for the MCC-Seq assay, with the following information:

Preferred label: "MethylC-Capture Sequencing" Alternative labels: "MCC-Seq", "Capture Methylome" Definition: "A next-generation sequencing approach in which a whole-genome sequencing library is prepared, bisulfite converted and amplified, followed by a capture enriching for targeted bisulfite-converted DNA fragments that are are subsequently identified by DNA sequencing".
Example: MethylC-Capture Sequencing approach was introduced as a cost-effective and customizable alternative method for large-scale interrogation of functionally-active methylomes while simultaneously providing genetic variation information in a proof-of-concept epigenome-wide association study of 72 obese individuals, identifying novel disease-associated variants.

Thanks in advance!

David

Reported by: dbujold

Original Ticket: obi/obi-terms/773

obi-bot commented 8 years ago

discussed on Jan 11, 2016 call. Will add if clearly distinct from existing subtypes.

Original comment by: cstoeckert

obi-bot commented 8 years ago

Original comment by: cstoeckert

obi-bot commented 8 years ago

David, I'm ready to add this to OBI but can you provide a definition source? Thanks for submitting this. Chris

Original comment by: cstoeckert

obi-bot commented 8 years ago

to follow up, can we use PMID: 26021296, Allum et al., Nature Commun. 2015?

Original comment by: cstoeckert

obi-bot commented 8 years ago

Hi Chris, yes, this is the right paper to use.

Thank you in advance,

David

On 01/23/2016 04:10 PM, Chris Stoeckert wrote:

to follow up, can we use PMID: 26021296, Allum et al., Nature Commun. 2015?


[obi-terms:#773] http://sourceforge.net/p/obi/obi-terms/773/ Adding a term for MCC-Seq

Status: open Group: general Created: Tue Jul 07, 2015 05:20 PM UTC by David Bujold Last Updated: Sat Jan 23, 2016 09:07 PM UTC Owner: Chris Stoeckert

Hello, I'd like to request a new ontology term for the MCC-Seq assay, with the following information:

Preferred label: "MethylC-Capture Sequencing" Alternative labels: "MCC-Seq", "Capture Methylome" Definition: "A next-generation sequencing approach in which a whole-genome sequencing library is prepared, bisulfite converted and amplified, followed by a capture enriching for targeted bisulfite-converted DNA fragments that are are subsequently identified by DNA sequencing". Example: MethylC-Capture Sequencing approach was introduced as a cost-effective and customizable alternative method for large-scale interrogation of functionally-active methylomes while simultaneously providing genetic variation information in a proof-of-concept epigenome-wide association study of 72 obese individuals, identifying novel disease-associated variants.

Thanks in advance!

David


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Original comment by: dbujold

obi-bot commented 8 years ago

Great! I'll add this term and close this item.

Original comment by: cstoeckert

obi-bot commented 8 years ago

Ok, thanks again!

David

On 01/25/2016 12:35 PM, Chris Stoeckert wrote:

Great! I'll add this term and close this item.


[obi-terms:#773] http://sourceforge.net/p/obi/obi-terms/773/ Adding a term for MCC-Seq

Status: open Group: general Created: Tue Jul 07, 2015 05:20 PM UTC by David Bujold Last Updated: Sat Jan 23, 2016 09:10 PM UTC Owner: Chris Stoeckert

Hello, I'd like to request a new ontology term for the MCC-Seq assay, with the following information:

Preferred label: "MethylC-Capture Sequencing" Alternative labels: "MCC-Seq", "Capture Methylome" Definition: "A next-generation sequencing approach in which a whole-genome sequencing library is prepared, bisulfite converted and amplified, followed by a capture enriching for targeted bisulfite-converted DNA fragments that are are subsequently identified by DNA sequencing". Example: MethylC-Capture Sequencing approach was introduced as a cost-effective and customizable alternative method for large-scale interrogation of functionally-active methylomes while simultaneously providing genetic variation information in a proof-of-concept epigenome-wide association study of 72 obese individuals, identifying novel disease-associated variants.

Thanks in advance!

David


Sent from sourceforge.net because you indicated interest in https://sourceforge.net/p/obi/obi-terms/773/

To unsubscribe from further messages, please visit https://sourceforge.net/auth/subscriptions/

Original comment by: dbujold

obi-bot commented 8 years ago

Original comment by: cstoeckert

obi-bot commented 8 years ago

Added to OBI.

Original comment by: cstoeckert