Phasmid D neuron
Phasmid D neuron left
Phasmid D neuron right
Textual definition
PHD
A neuron class of 2 bilateral, cholinergic, peptidergic, male-specific, ciliated neurons generated by transdifferentiation from a male PHso1 glial cell in the late L4 larval stage of a male C. elegans animal.
PHDL
The left PHD neuron of the pair of bilateral PHD neurons in a male C. elegans animal.
PHDR
The right PHD neuron of the pair of bilateral PHD neurons in a male C. elegans animal.
"Together, these data demonstrate that the male PHso1 glial cells transdifferentiate into a novel class of ciliated neurons which we have termed phasmid D neurons (PHDs)."
"The data presented here extend John Sulston’s original observations and demonstrate that male PHso1 cells undergo a direct glia-to-neuron transdifferentiation to produce a novel class of bilateral cholinergic, peptidergic and ciliated sensory neurons, the phasmid D neurons."
chris-grove
commented
4 years ago
Preferred term label
PHD PDHL PDHR
Synonyms
Phasmid D neuron Phasmid D neuron left Phasmid D neuron right
Textual definition
PHD A neuron class of 2 bilateral, cholinergic, peptidergic, male-specific, ciliated neurons generated by transdifferentiation from a male PHso1 glial cell in the late L4 larval stage of a male C. elegans animal.
PHDL The left PHD neuron of the pair of bilateral PHD neurons in a male C. elegans animal.
PHDR The right PHD neuron of the pair of bilateral PHD neurons in a male C. elegans animal.
Paper in review at eLife; BoRXiv preprint here: https://www.biorxiv.org/content/biorxiv/early/2019/05/01/285320.full.pdf
"Together, these data demonstrate that the male PHso1 glial cells transdifferentiate into a novel class of ciliated neurons which we have termed phasmid D neurons (PHDs)."
"The data presented here extend John Sulston’s original observations and demonstrate that male PHso1 cells undergo a direct glia-to-neuron transdifferentiation to produce a novel class of bilateral cholinergic, peptidergic and ciliated sensory neurons, the phasmid D neurons."
Suggested parent term
ciliated neuron (WBbt:0006816) male-specific (WBbt:0005757) cholinergic neuron (WBbt:0006840)