search

obophenotype / cell-ontology

An ontology of cell types
https://obophenotype.github.io/cell-ontology/
Creative Commons Attribution 4.0 International
140 stars 49 forks source link

cells classified under 'supporting cell of cochlea' should be under 'organ of corti supporting cell' #1269

Open cmungall opened 2 years ago

cmungall commented 2 years ago

Find the dual support cell groupings dubious.

(note the parallel structure in Uberon is a located-in-part-of chain, see https://github.com/obophenotype/uberon/issues/1905)

This is a single-child by axis of classification, which is a bad smell

image

claudius cells are in the organ of corti https://en.wikipedia.org/wiki/Claudius_cell

interdental cells are located in the top of the limbus, are epithelial cells that anchor the tectorial membrane, a gelatinous structure secreted by the interdental cells that connects to the organ of Corti. It is important for the coupling of sound-induced vibrations to the hair cell stereocilia https://www.frontiersin.org/articles/10.3389/fneur.2020.580639/full

I didn't check the others but I suspect there may not be justification for the two classes and a simpler classification is possible

See also https://github.com/mgijax/mammalian-phenotype-ontology/issues/3458

See also #2 - having more upper level disjointness axioms in CL as we do in uberon would help here. E.g. epithelial cell and bone cell

github-actions[bot] commented 2 years ago

This issue has not seen any activity in the past 6 months; it will be closed automatically in one year from now if no action is taken.