obophenotype / cell-ontology

An ontology of cell types
https://obophenotype.github.io/cell-ontology/
Creative Commons Attribution 4.0 International
146 stars 49 forks source link

[NTR] multiple neurotransmitters neuron for BICAN Basal Ganglia #2579

Open AvolaAmg opened 2 months ago

AvolaAmg commented 2 months ago

@JABelfiore please review

multiple neurotransmitters neuron:

definition: A central nervous system neuron that is capable of releasing multiple primary neurotransmitters and neuromodulators.

database_cross_reference: PMID: 24816154 PMID: 24319410

uberon term: central nervous system

parent term: central nervous system neuron

For this term I need to create a new property multiple neurotransmitter secretion which is similar to neurotransmitter secretion

dosumis commented 2 months ago

This is quite abstract. Might it be sufficient to just add classes for neurons with known combos of NTs?

Also - does including neuromodulators potentially make it too broad?

AvolaAmg commented 2 months ago

I am planning on writing subclasses for this based on the neurotransmitter combination, to have more specific child terms.

I can include specific neurotransmitters and neuromodulators in this definition to avoid ambiguity.