obophenotype / cell-ontology

An ontology of cell types
https://obophenotype.github.io/cell-ontology/
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review ependymoglial cell #2596

Open dosumis opened 1 month ago

dosumis commented 1 month ago

rdfs:label "ependymoglial cell" (CL_0000683) definition "A cell that transports hormones from neurosecretory cells. This nerve cell is characterized by bipolar shape and endfeet that contact a basal lamina around blood vessels, and/or the pia mater or vitreous body of the eye and additionally contact the ventricular surface or sub-retinal space."

image

https://bioportal.bioontology.org/ontologies/SAO/?p=classes&conceptid=http%3A%2F%2Fccdb.ucsd.edu%2FSAO%2F1.2%23sao3593465546&jump_to_nav=true

A type of nerve cell characterized by bipolar shape and endfeet that contact a basal lamina around blood vessels, and/or the pia mater or vitreous body of the eye and additionally contact the ventricular surface or sub-retinal space. (Reichenbach and Wolburg, 2nd edition, 2005)

This is currently the sole parent of tanycyte. The term is often used synonymously with ependymal cell - which in turn may be used broadly to refer to the cells that make up the ependymal epithelium or more narrowly to refer only to the cells that secrete CSF (Choroid plexus cells) and multicilliated ependymal cells. SAO classification fits with this, but the text definition does not. Some aspects are similar to tanycyte, but there is also reference to the eye. Is this term justified as a grouping term covering tanycytes and similar cells elsewhere?

TODO - Find if there are other cells that could go under ependymoglial cell and if not merge with tanycyte.