search

obophenotype / cell-ontology

An ontology of cell types
https://obophenotype.github.io/cell-ontology/
Creative Commons Attribution 4.0 International
145 stars 49 forks source link

[NTR-cxg] myotendinous junction #2676

Open sebozzie opened 1 week ago

sebozzie commented 1 week ago

Please check that the term does not already exist by using the ontology search tool OLS: https://www.ebi.ac.uk/ols4/ontologies/cl

Preferred term label myotendinous junction

Synonym(s) (add reference(s), please) myotendinous junction nuclei https://doi.org/10.1038/s41467-020-20063-w MTJ https://doi.org/10.1038/s41467-020-18789-8 MTJ nuclei https://doi.org/10.1038/s41467-020-20064-9

Definition Myotendinous junction nuclei are specialized muscle nuclei located at the interface where muscle fibers connect to tendons. These myonuclei help regulate the structural integrity and function of the muscle-tendon connection, playing a key role in transmitting the force generated by muscle contraction to the tendon.

Parent cell type term CL:0008046: extrafusal muscle fiber

Anatomical structure where the cell type is found UBERON:0001134: skeletal muscle tissue

Your ORCID 0009-0001-6947-615X

Additional notes or concerns

https://doi.org/10.1038/s41467-020-20063-w: "Myotendinous junction (MTJ) nuclei ... were notable for expression of Col22a1 ..."

dosumis commented 3 days ago

GO has myotendenous junction GO:0005927

suggested label: myotendenous junction nucleus Suggested EC def: 'GO:nucleus and part_of some 'CL:0008046; extrafusal muscle fiber' and overlaps some 'GO:0005927; myotendenous junction'