Open sebozzie opened 1 week ago
GO has myotendenous junction GO:0005927
suggested label: myotendenous junction nucleus Suggested EC def: 'GO:nucleus and part_of some 'CL:0008046; extrafusal muscle fiber' and overlaps some 'GO:0005927; myotendenous junction'
Please check that the term does not already exist by using the ontology search tool OLS: https://www.ebi.ac.uk/ols4/ontologies/cl
Preferred term label myotendinous junction
Synonym(s) (add reference(s), please) myotendinous junction nuclei https://doi.org/10.1038/s41467-020-20063-w MTJ https://doi.org/10.1038/s41467-020-18789-8 MTJ nuclei https://doi.org/10.1038/s41467-020-20064-9
Definition Myotendinous junction nuclei are specialized muscle nuclei located at the interface where muscle fibers connect to tendons. These myonuclei help regulate the structural integrity and function of the muscle-tendon connection, playing a key role in transmitting the force generated by muscle contraction to the tendon.
Parent cell type term CL:0008046: extrafusal muscle fiber
Anatomical structure where the cell type is found UBERON:0001134: skeletal muscle tissue
Your ORCID 0009-0001-6947-615X
Additional notes or concerns
https://doi.org/10.1038/s41467-020-20063-w: "Myotendinous junction (MTJ) nuclei ... were notable for expression of Col22a1 ..."