obophenotype / cell-ontology

An ontology of cell types
https://obophenotype.github.io/cell-ontology/
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[NTR] fallopian tube smooth muscle cell #2682

Closed Caroline-99 closed 1 month ago

Caroline-99 commented 1 month ago

Please check that the term does not already exist by using the ontology search tool OLS: https://www.ebi.ac.uk/ols4/ontologies/cl

This term was requested in the Reproductive System Jamboree.

Preferred term label fallopian tube smooth muscle cell

Synonyms (add reference(s), please) oviduct smooth muscle cell -exact (PMID: 31613440) uterine tube smooth muscle cell -exact (PMID: 31613440)

Definition (free text, with reference(s), please. PubMed ID format is PMID:XXXXXX) A smooth muscle cell that is part of the fallopian tube. This cell is responsible for peristaltic contractions that facilitate gamete and embryo transport, fluid mixing, and embryo admission to the uterus.

PMID: 31613440 PMID: 31183831

Comments Fallopian tube smooth muscle cell in the human contracts dynamically in response to hormones and signaling molecules. Prostaglandins, particularly PGF2α and PGE2, have been shown to increase muscular contractions, while progesterone, levonorgestrel, mifepristone, oxytocin, and human chorionic gonadotropin (hCG) decrease them. These contractile responses are crucial for regulating gamete and embryo transport through the fallopian tube. PMID: 18621753

Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols4/ontologies/cl) smooth muscle cell

Anatomical structure where the cell type is found (check Uberon for anatomical structures: https://www.ebi.ac.uk/ols4/ontologies/uberon) fallopian tube Your ORCID

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