issues
search
obophenotype
/
cell-ontology
An ontology of cell types
https://obophenotype.github.io/cell-ontology/
Creative Commons Attribution 4.0 International
146
stars
49
forks
source link
Fixes #2732 ntr cxg atretic theca cell
#2733
Closed
Caroline-99
closed
2 weeks ago
Caroline-99
commented
2 weeks ago
Fixes #2732
Caroline-99
commented
2 weeks ago
gogoeditdiff
github-actions[bot]
commented
2 weeks ago
Here's a diff of how these changes impact the classified ontology (on -base file):
# Ontology comparison ## Left - Ontology IRI: `http://purl.obolibrary.org/obo/cl/cl-base.owl` - Version IRI: `http://purl.obolibrary.org/obo/cl/releases/2024-11-06/cl-base.owl` - Loaded from: `file:/__w/cell-ontology/cell-ontology/src/ontology/cl-base-master.owl/cl-base.owl` ## Right - Ontology IRI: `http://purl.obolibrary.org/obo/cl/cl-base.owl` - Version IRI: `http://purl.obolibrary.org/obo/cl/releases/2024-11-06/cl-base.owl` - Loaded from: `file:/__w/cell-ontology/cell-ontology/src/ontology/cl-base-pr.owl/cl-base.owl` ### Ontology imports ### Ontology annotations ### atretic theca cell `http://purl.obolibrary.org/obo/CL_4052027` #### Added - [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) [contributor](http://purl.org/dc/terms/contributor) [0009-0000-8480-9277](https://orcid.org/0009-0000-8480-9277) - [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "During atresia, theca interna and externa cells undergo distinct morphological and functional changes. Theca interna cells round up, expand in cytoplasmic area, and thicken the internal layer as organization degrades, while showing reduced STAR expression, which lowers androgen production. Theca externa cells display decreased ACTA2 expression, weakening structural integrity." - [hasDbXref](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:38069168" - [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) [label](http://www.w3.org/2000/01/rdf-schema#label) "atretic theca cell" - [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) [IAO_0000115](http://purl.obolibrary.org/obo/IAO_0000115) "A theca cell undergoing atresia, characterized by distinct morphological changes including hypertrophy, altered cell shape, and disrupted layered organization. This cell exhibits reduced steroidogenic capacity and changes in surrounding vascularization. The onset of theca cell atresia can vary, occurring at different stages of follicle atresia depending on the phase of folliculogenesis." - [hasDbXref](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20628033" - [hasDbXref](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:38069168" - [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) [date](http://purl.org/dc/terms/date) "2024-11-06T10:10:51Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) - Class: [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) - [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) SubClassOf [atretic follicular cell of ovary](http://purl.obolibrary.org/obo/CL_4033089) - [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) SubClassOf [RO_0002202](http://purl.obolibrary.org/obo/RO_0002202) some [theca cell](http://purl.obolibrary.org/obo/CL_0000503)
github-actions[bot]
commented
2 weeks ago
Here's a diff of your edit file (unreasoned)
# Ontology comparison ## Left - Ontology IRI: `http://purl.obolibrary.org/obo/cl.owl` - Version IRI: *None* - Loaded from: `file:/__w/cell-ontology/cell-ontology/master/src/ontology/cl-edit.owl` ## Right - Ontology IRI: `http://purl.obolibrary.org/obo/cl.owl` - Version IRI: *None* - Loaded from: `file:/__w/cell-ontology/cell-ontology/branch/src/ontology/cl-edit.owl` ### Ontology imports ### Ontology annotations ### atretic theca cell `http://purl.obolibrary.org/obo/CL_4052027` #### Added - [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) [contributor](http://purl.org/dc/terms/contributor) [0009-0000-8480-9277](https://orcid.org/0009-0000-8480-9277) - [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "During atresia, theca interna and externa cells undergo distinct morphological and functional changes. Theca interna cells round up, expand in cytoplasmic area, and thicken the internal layer as organization degrades, while showing reduced STAR expression, which lowers androgen production. Theca externa cells display decreased ACTA2 expression, weakening structural integrity." - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:38069168" - [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) [label](http://www.w3.org/2000/01/rdf-schema#label) "atretic theca cell" - [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A theca cell undergoing atresia, characterized by distinct morphological changes including hypertrophy, altered cell shape, and disrupted layered organization. This cell exhibits reduced steroidogenic capacity and changes in surrounding vascularization. The onset of theca cell atresia can vary, occurring at different stages of follicle atresia depending on the phase of folliculogenesis." - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:38069168" - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:20628033" - [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) [date](http://purl.org/dc/terms/date) "2024-11-06T10:10:51Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) - Class: [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) - [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) SubClassOf [atretic follicular cell of ovary](http://purl.obolibrary.org/obo/CL_4033089) - [atretic theca cell](http://purl.obolibrary.org/obo/CL_4052027) SubClassOf [develops from](http://purl.obolibrary.org/obo/RO_0002202) some [theca cell](http://purl.obolibrary.org/obo/CL_0000503) ### ovarian follicle atresia `http://purl.obolibrary.org/obo/GO_0001552` #### Added - Class: [ovarian follicle atresia](http://purl.obolibrary.org/obo/GO_0001552)
Caroline-99
commented
2 weeks ago
gogoeditdiff
Fixes #2732