obophenotype / cell-ontology

An ontology of cell types
https://obophenotype.github.io/cell-ontology/
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[NTR] respiratory airway secretory cell #2749

Open dosumis opened 2 weeks ago

dosumis commented 2 weeks ago

Preferred term label respiratory airway secretory cell

Synonyms (add reference(s), please)

RAS

Definition (free text, with reference(s), please. PubMed ID format is PMID:XXXXXX)

Secretory epithelial cell of the respiratory and terminal bronchioles.

Possible additional text: These cells are non-ciliated, contain secretory granules and are transcriptomically distinct from other epithelial cell types in the same location.

Murthy et al https://pmc.ncbi.nlm.nih.gov/articles/PMC9169066/ Rustam et al https://pubmed.ncbi.nlm.nih.gov/36796082/ Basil et al https://www.nature.com/articles/s41586-022-04552-0

Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols4/ontologies/cl)

secretory epithelial cell

Anatomical structure where the cell type is found (check Uberon for anatomical structures: https://www.ebi.ac.uk/ols4/ontologies/uberon)

'epithelium of bronchiole' UBERON_0002051

We have no grouping term for respiratory + terminal bronchiole.

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Your ORCID

Additional notes or concerns

Notes: This term groups various distinguishable types - as described in Murthy and Rustam. See also tentative hierarchy here:

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