The current definition of a 'progenitor cell of endocrine pancreas' is a
multi-fate stem cell is wrong. Generally stem cells give rise to progenitor
cells so the is_a relation seems wrong. For this specific case, the cells
generating islet cells and expressing neurogenin-3 and Isl1 are transitory and
don't represent a population of cells that 'proliferate throughout life to
provide progenitor cells'. See for example section 4 on page 679 in Rieck,
Bankaitis, and Wright Lineage determinants in early endocrine development.
Seminars in Cell & Developmental Biology 23 (2012) 673-684.
Original issue reported on code.google.com by stoec...@upenn.edu on 1 Jul 2013 at 7:03
[x] Make 'progenitor cell of endocrine pancreas' a subclass of 'progenitor cell' (which develops_from some stem cell), instead of 'multi-fate stem cell'
Original issue reported on code.google.com by
stoec...@upenn.edu
on 1 Jul 2013 at 7:03