search

obophenotype / cell-ontology

An ontology of cell types
https://obophenotype.github.io/cell-ontology/
Creative Commons Attribution 4.0 International
145 stars 49 forks source link

CL:0000446, chief cell of parathyroid gland #991

Open ANiknejad opened 3 years ago

ANiknejad commented 3 years ago

CL:0000446

has synonym: "parathyroid hormone secreting cell" EXACT [] and ZFA:0009207 'parathyroid hormone secreting cell' does not have xref to CL:0000446

The issue is that CL:0000446 is_a: CL:0002260 ! epithelial cell of parathyroid gland

but ZFA is not supposed to have a true parathyroid gland, while PTH is detected in many zebrafish tissues, see https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133784/

Maybe changing the name of CL:0000446 from 'chief cell of parathyroid gland' to its synonym 'parathyroid hormone secreting cell' will let integrate ZFA:0009207 into Uberon? (and adding taxon constraint to is_a: CL:0002260 ! epithelial cell of parathyroid gland)

fbastian commented 3 years ago

Alternatively, create a new class 'parathyroid hormone secreting cell', and CL:0000446 could become intersection_of: CL:XXX ! parathyroid hormone secreting cell' intersection_of: part_of UBERON:0001132 ! parathyroid gland