Anti-Recoverin antibody

[carolina-f]

Preferred term label:

Synonyms

Anti-retinal CAR antigen antibody

Definition (free text, please give PubMed ID) The presence of autoantibodies in the serum that react against recoverin. Recoverins are calcium-binding proteins primarily expressed in retinal rod photoreceptors and primarily involved in phototransduction.

PMID: 38054667 Anti-recoverin antibodies are typically found in cancer-associated retinopathy (CAR) or autoimmune diseases. We present a case of anti-recoverin positive cerebellar syndrome without any signs of malignancy or retinopathy. The patient was treated with steroids and intravenous immunoglobulins, improving cognitive and motor symptoms.

Parent term (use hpo.jax.org/app) Autoimmune antibody positivity HP:0030057

Diseases characterized by this term ? (e.g. Orphanet or OMIM number) ORPHA:71505 Cancer-associated retinopathy

Your nano-attribution (ORCID) 0009-0005-6714-5727

[pnrobinson]

@carolina-f Adding new term:

• ID: HP:6000882
• label: Anti-recoverin antibody positivity
• parents: Autoimmune antibody positivity (HP:0030057)
• pmid: PMID:38054667
• def: The presence of autoantibodies in the serum that react against recoverin. Recoverins are calcium-binding proteins primarily expressed in retinal rod photoreceptors and primarily involved in phototransduction.
• comment:
• orcid: orcid:0009-0005-6714-5727
• github ID: https://github.com/obophenotype/human-phenotype-ontology/issues/10549
• synonyms: Anti-retinal CAR antigen antibody(NONE)