obophenotype / human-phenotype-ontology

Ontology for the description of human clinical features
http://obophenotype.github.io/human-phenotype-ontology/
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Punctate palmar and solar hyperkeratosis (HP_0007508) #1127

Closed pnrobinson closed 7 years ago

pnrobinson commented 7 years ago

This is a bundled term and should be debundled

pnrobinson commented 7 years ago

This HPO term is currently used to annotate the disease

http://www.omim.org/entry/106400

The two entities are 1) A solar keratosis is a small, thickened, scaly growth which develops on the skin. It is the most common skin condition resulting from sun-damaged skin. It is caused by excessive exposure to ultraviolet (UV) rays from the sun over many years. Solar keratoses are also known as actinic keratoses. Each can range from the size of a pinhead to 2-3 cm across. Their colour can be light, dark, pink, red, the same colour as your skin, or a combination of these. The top of each one may have a yellow-white, scaly crust. Redness may develop in the surrounding skin. The picture shows a solar keratosis on an ear.

Solar keratoses feel rough and dry, and are slightly raised from the surface of the skin. Often it is easier to feel rather than see them. They can also be hard and warty. Sometimes hard skin grows out of a solar keratosis like a horn (called a cutaneous horn).

and

2) punctate palamar hyperkeratosis -- tiny bumps of thickened skin on the palms and soles and usually appears in late childhood or early adulthood.

pnrobinson commented 7 years ago

The OMIM entry describes a single family and has not been updated in over 15 years. Since solar keratosis may occur simply owing to exp[osure to the sun, it does not seem necessary for this featureto berelated to whateverdisease the family had. I am going to define this term as punctate palmar hyperkeratosis, and add a new term request for solar hyperkeratosis.