obophenotype / human-phenotype-ontology

Ontology for the description of human clinical features
http://obophenotype.github.io/human-phenotype-ontology/
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ENR-EYE NTR: Increased tear production #2752

Closed pnrobinson closed 6 years ago

pnrobinson commented 6 years ago

[added] Added//Increased tear production//new term request (PS); parent- Increased lacrimation [level: 7]; term- Increased tear production [level: 8]

pnrobinson commented 6 years ago

@psergouniotis Is this different from increased lacrimation (defined as Abnormally increased lacrimation, that is, excessive tearing (watering eye).?

psergouniotis commented 6 years ago

Yes they are different.

Firstly, "Increased lacrimation" should be renamed to 'Epiphora" (with "Increased lacrimation" kept as a synonym).

Secondly the following structure is proposed: Epiphora   | Increased tear production   |   | Increased basal tear production   |   | Reflex tearing   | Lacrimal pump failure   | Decreased tear drainage

Further to your question, you can have "Increased lacrimation" (epiphora) roughly due to either too many tears being produced (Increased tear production) or to not enough tear being drained away (Decreased tear drainage). Therefore, "Increased tear production" should be a subclass and not a synonym of "Increased lacrimation" (Epiphora)

pnrobinson commented 6 years ago

Adding term for Increased tear production with definition: Increased lacrimation owing to overproduction of tears.

pnrobinson commented 6 years ago

@psergouniotis Can you provide definitions for

pnrobinson commented 6 years ago

@psergouniotis I am adding this definition for Lacrimal pump failure: Reduced tear outflow is due to tear pump dysfunction and associated with increased tearing. -- is it OK?

pnrobinson commented 6 years ago

@psergouniotis Can you provide a definition for Decreased tear drainage. Is it a synonym of Nasolacrimal duct obstruction (NLDO) ?

pnrobinson commented 6 years ago

@psergouniotis The definition for Lacrimal pump failure is OK and was added.

psergouniotis commented 6 years ago

Proposed definitions:

"Decreased tear drainage" may be associated with Nasolacrimal sac obstruction & Nasolacrimal duct obstruction. However, not all obstructions will cause decreased tear drainage and therefore I think it would be best not to have these associated (one could select both "Nasolacrimal sac obstruction" and "Decreased tear drainage")

LCCarmody commented 6 years ago

Added definitions to Increased basal tear production, Reflex tearing, and Updated lacrimal pump failure. I left 'Decrease tear drainage' because I am not sure where it should be located. See issue #2756

LCCarmody commented 6 years ago

Going to close this issue since there is another issue open about this topic.