Loinc 20402-4: "CD16+CD56+ cells [#/volume] in Blood"

obophenotype / human-phenotype-ontology

Ontology for the description of human clinical features

http://obophenotype.github.io/human-phenotype-ontology/

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Loinc 20402-4: "CD16+CD56+ cells [#/volume] in Blood" #3643

Closed pnrobinson closed 5 years ago

pnrobinson commented 6 years ago

Suggest creating a new term for Loinc: 20402-4 [CD16+CD56+ cells [#/volume] in Blood] New term label: New term comment (if any): Your biocurator ID for loinc2hpo (if desired): HPO:probinson

pnrobinson commented 5 years ago

These can be markers for natural killer cells https://www.ncbi.nlm.nih.gov/pubmed/11252817

pnrobinson commented 5 years ago

Three distinct subsets of NK cells are recognized in human peripheral blood; CD56bri, CD56dim and CD56neg; categorized according to the expression of NK cell lineage markers CD56 and CD16 [20,21]. CD56bri are pre-dominantly cytokine producing cells and CD56dim are mainly cytotoxic [22]. (from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915033/)

pnrobinson commented 5 years ago

However, these markers are not sufficient I think to define a cell type. I do not think we can annotate this test at this time.