obophenotype / human-phenotype-ontology

Ontology for the description of human clinical features
http://obophenotype.github.io/human-phenotype-ontology/
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Please revise textdef of HP:0030158 (Cervical ectropion) #4911

Closed drseb closed 5 years ago

drseb commented 5 years ago

HPO term

HP:0030158 (Cervical ectropion)

Suggested revision of textual definition

Very hard to read and not really understandable by our translators:

Eversion of the endocervix with protrusion of the central (endocervical) columnar epithelium through the external os of the cervis into the vaginal milieu

Make it two sentences? Add a few words?

pnrobinson commented 5 years ago

Cervical ectropion [which is also called cervical ectopy or erosion] occurs when eversion of the endocervix exposes columnar epithelium to the vaginal milieu (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307624/) Comment: Cervical ectropion is the presence of columnar cells on the ectocervix, which is normally composed of a squamous epithelium. Potential causes of ectropion include adolescent age, pregnancy, and hormonal contraceptives.5 Some clinicians believe ectropion could be a normal asymptomatic variant, whereas others believe it to be correlated with chronic cervicitis.5 The presence of the metaplastic columnar epithelium can manifest a myriad of symptoms including increased vaginal discharge, leukorrhea, postcoital bleeding, pelvic pain, recurrent cervicitis, and dyspareunia.(https://www.ncbi.nlm.nih.gov/pubmed/28460993) Comment: The upper cervix (endocervix) is lined by a simple columnar epithelium that contains mucous-secreting cells. In contrast, the lower cervix (ectocervix) is lined by a stratified squamous epithelium. The transition point between these two epithelia is known as the external os.

pnrobinson commented 5 years ago

done