Reason for deprecation
Obstructive lung disease is a more a general term and describes a disease not a single characteristic feature.
Suggested replacement or term to consider
Airflow obstruction is typically assessed by spirometry. Individuals with airflow obstruction have reductions in the forced expiratory volume at 1 s (FEV1) and in the ratio of FEV1 to forced vital capacity (FVC). Can be described by existing HPO terms: Reduced FEV1/FVC ratio (HP:0030877), Reduced forced expiratory volume in one second (HP:0032342), additional features are Chronic bronchitis (HP:0004469), Emphysema (HP:0002097)
terms can be linked to disease via OMIM: 606963 (COPD), 613490 (Alpha 1 Antitrypsin deficiency), and to genetic associations (SERPINA1 OMIM:107400, TGFB1 OMIM: 190180)
HPO term Obstructive lung disease (HP: 0006536)
Reason for deprecation Obstructive lung disease is a more a general term and describes a disease not a single characteristic feature.
Suggested replacement or term to consider Airflow obstruction is typically assessed by spirometry. Individuals with airflow obstruction have reductions in the forced expiratory volume at 1 s (FEV1) and in the ratio of FEV1 to forced vital capacity (FVC). Can be described by existing HPO terms: Reduced FEV1/FVC ratio (HP:0030877), Reduced forced expiratory volume in one second (HP:0032342), additional features are Chronic bronchitis (HP:0004469), Emphysema (HP:0002097)
terms can be linked to disease via OMIM: 606963 (COPD), 613490 (Alpha 1 Antitrypsin deficiency), and to genetic associations (SERPINA1 OMIM:107400, TGFB1 OMIM: 190180)
PubMed: 15175276, 11914989
nano-attribution LMU crapp, @mgriese, @katrinknoflach