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Ontology for the description of human clinical features
http://obophenotype.github.io/human-phenotype-ontology/
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Dependence on diaphragmatic breathing #5900

Closed JillMiller closed 3 years ago

JillMiller commented 4 years ago

Preferred term label: Dependence on diaphragmatic breathing

Synonyms

Definition (free text, please give PubMed ID) Reduced ability for thoracic breathing leading to a dependence on diaphragmatic breathing.

Parent term (use hpo.jax.org/app) Intercostal muscle weakness HP:0004878; Functional respiratory abnormality HP:0002795

Diseases characterized by this term ? (e.g. Orphanet or OMIM number)

Your nano-attribution (ORCID)

pnrobinson commented 3 years ago

@Aggriese I cannot find a good PubMed reference for this feature. Since diaphragmatic breathing is the norm, I am not sure if Dependence on diaphragmatic breathing is a good term name, and wonder if weakened thoracic breathing or something like that would be more accurate.

mgriese commented 3 years ago

The term is useful in the context of spinal cord injury. C5 to C6 spinal lesions have alterations of the intercostal and abdominal wall muscles, however the diaphragm (C3-C5) is intact. Thus patients can rely on their diaphragmatic function and do not need ventilatory support.

pnrobinson commented 3 years ago

@mgriese I think this is basically a synonym of this Intercostal muscle weakness HP:0004878 https://hpo.jax.org/app/browse/term/HP:0004878

mgriese commented 3 years ago

Diaphragmatic would (usually) not coded as intercostal; these are 2 different level of the respiratory driving force.

pnrobinson commented 3 years ago

I mean if you have (severe) Intercostal muscle weakness then you are going to be dependent on diaphragmatic beathing.

mgriese commented 3 years ago

Ok, I understand, thought: synonym...

pnrobinson commented 3 years ago

I will add this as a related synonym to https://hpo.jax.org/app/browse/term/HP:0004878