NTR: Impaired ability to shift

[nicolevasilevsky]

Preferred term label: Impaired ability to shift

Synonyms Sticky behavior Inflexible behavior - broad Impaired set shifting

Definition (free text, please give PubMed ID) A behavioral abnormality whereby a person is unable to move freely from one situation, activity or aspect of aa problem to another as circumstances demand. Key aspects of shifting include the ability to make transitions, problem solve flexibly, switch or alternate attention, and change focus from one mind-set or topic to another. Mild deficits in the ability to shift compromise the efficiency of problem solving, whereas more severe difficulties are reflected in perseverative behaviors. Sometimes this is described as being rigid or inflexible. Source: updated this is from the BRIEF manual, noted below.

Here is an alternative definition: An impairment in executive functioning whereby there is an inability to modify attention and behavior in response to changing circumstances and demands. Source: PMID:26039846

Parent term (use hpo.jax.org/app) Impaired executive functioning

Diseases characterized by this term ? (e.g. Orphanet or OMIM number) Autism spectrum disorder

This is needed fo the Kids First INCLUDE supplement.

[pnrobinson]

@nicolevasilevsky Can you ask Stephanie for a more precise label. To shift could be interpreted as shifting a physical object. Also, please let's try to get PMIDs for references!

[nicolevasilevsky]

Stephanie checked with an expert Lisa Jacobson, and Lisa recommends “inflexibility” or “sticky” as the primary label.

I asked Stephanie to ask Lisa for a citation for the reference, she is out of office until Aug 09, so we may not hear back right away.

Thanks!

[nicolevasilevsky]

@pnrobinson this is the publication info for the BRIEF2 manual. Not sure how to reference this in Protege?

https://www.parinc.com/Products/Pkey/4523

[pnrobinson]

If there is no other way, them we can use an ISBN, but this is not that useful as a reference since it cannot be accessed by most users. We should try to find a PMID!

[nicolevasilevsky]

I updated the suggested def above, with a PMID

[pnrobinson]

I would suggest we use the above PMID but with the label "Inability to shift focus"

@bcoleman96 thoughts?

[nicolevasilevsky]

I like this label suggestion

[bcoleman96]

I agree. "Inability to shift attention" might be better since set-shifting might be considered an inability to focus.

In terms of the definition, have we already had a discussion about set shifting vs cognitive shifting? There seems to be some debate on whether these are different things or just often confused.

I would also suggest "impaired task shifting" or "inability to task shift" as synonyms.

[pnrobinson]

adding this term with this ref https://pubmed.ncbi.nlm.nih.gov/23356593/

label Impaired ability to shift attention