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obophenotype / human-phenotype-ontology

Ontology for the description of human clinical features
http://obophenotype.github.io/human-phenotype-ontology/
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adipocyte hypertrophy #625

Closed pnrobinson closed 8 years ago

pnrobinson commented 8 years ago

See http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105262 for references and definitions

pnrobinson commented 8 years ago

Def: An increase in mean adipocyte cell size. This feature can be measured by determining the average cell diameter of adipocytes microscopically using abdominal subcutaneous adipose tissue obtained by biopsy. PMID:25148116

comment Adipose tissue expansion occurs mainly through two processes; expansion of existing adipocytes (hypertrophy) and/or recruitment of new adipocytes (hyperplasia).