obophenotype / human-phenotype-ontology

Ontology for the description of human clinical features
http://obophenotype.github.io/human-phenotype-ontology/
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NTR, pulmo: Necrotizing pulmonary granulomatosis #6385

Closed GrieseAG closed 3 years ago

GrieseAG commented 3 years ago

Preferred term label: Necrotizing pulmonary granulomatosis

Synonyms caseating pulmonary granulomatosis

Definition (free text, please give PubMed ID) A granuloma that is associated with necrotic changes. Caseation necrosis is defined as a region in granulomas with eosinophilic, granular and cheese-like cellular debris with necrosis. The word caseous itself means "pertaining or related to cheese", and comes from the Latin word caseus, meaning cheese. Comment: In HE staining, it is characterized by acellular pink areas of necrosis surrounded by a granulomatous inflammatory process.

Parent term (use hpo.jax.org/app) Pulmonary granulomatosis HP:0030250

Diseases characterized by this term ? (e.g. Orphanet or OMIM number) Necrotizing sarcoid granulomatosis (PMID: 26040776), Tuberculosis (TB; ORPHA:3389), fungal infections (Hot tube lung)

Your nano-attribution (ORCID) LMU:chrapp, @kknoflach, @mgriese

pnrobinson commented 3 years ago

added term