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obophenotype / human-phenotype-ontology

Ontology for the description of human clinical features
http://obophenotype.github.io/human-phenotype-ontology/
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NTR, pulmo: alveolar septal thickening #6395

Closed GrieseAG closed 3 years ago

GrieseAG commented 3 years ago

Preferred term label: (non-fibrotic?) alveolar septal thickening

Synonyms Alveolar septal thickening without fibrosis

Definition (free text, please give PubMed ID) thickening of alveolar septa without significant cellular infiltrate

ISBN 978-1-4511-7643-8 (alk. paper) Churg, Andrew, and Churg. Atlas of Interstitial Lung Disease Pathology : Pathology with High Resolution CT Correlations, Wolters Kluwer, 2013.

Parent term (use hpo.jax.org/app) Abnormal pulmonary alveolar system morphology HP:0033137 Pulmonary interstitial high-resolution computed tomography abnormality HP:0025389

Diseases characterized by this term ? (e.g. Orphanet or OMIM number)

Your nano-attribution (ORCID) LMU:chrapp, @kknoflach, @mgriese

pnrobinson commented 3 years ago

This is related to this term -- https://hpo.jax.org/app/browse/term/HP:0030879 can we discuss how to represent this?

pnrobinson commented 3 years ago

This should be the (distinct) histo finding

pnrobinson commented 3 years ago

One question -- if the term is Alveolar septal thickening without fibrosis, then I do not understand why the definition ("without significant cellular infiltrate") is correct -=- if we do not have more cells or more scarring, then what is the correlate of the thickening?

pnrobinson commented 3 years ago

-single parent : Abnormal pulmonary alveolar system morphology HP:0033137

put https://hpo.jax.org/app/browse/term/HP:0025176 under HRCT hierarchy

pnrobinson commented 3 years ago

added