Closed GrieseAG closed 3 years ago
child terms: exogenous LP: Lipid comes from the outside, for example by inhaling aromatic oil
endogenous LP: Lipid occurs from the body itself. when an airway is obstructed, it is often the case that distal to the obstruction, lipid-laden macrophages and giant cells fill the lumen of the disconnected airspace
It seems these are diseases that also have characteristic phenotypic features that distinguish them from other forms of pneumonia https://www.ajronline.org/doi/10.2214/AJR.09.3040 e.g., Characteristically, chronic exogenous lipoid pneumonia manifests as an adipose-containing mass [1] (Fig. 8). Although the mass is typically irregular or spiculated as a result of chronic inflammation and secondary fibrosis, the presence of fat in the mass is, with a few exceptions, a diagnostic feature of exogenous lipoid pneumonia.
Endogenous lipoid pneumonia is a histopathologic diagnosis made on the basis of the characteristic appearance of the obstructive pneumonitis. Macroscopically, there is parenchymal consolidation that has a characteristic yellowish discoloration due to the accumulation of lipid in the alveoli [18]. Histologically, there is an accumulation of lipid-filled macrophages and eosinophilic proteinaceous material derived from degenerating cells, including surfactant from type II pneumocytes, in the alveoli distal to the bronchial obstruction.
Added terms. Note that it is "lipoid" (with o) Pneumonia.
Preferred term label: Lipid pneumonia
Synonyms Cholesterol Pneumonia
Definition (free text, please give PubMed ID) Specific form of lung inflammation that develops when lipids enter the bronchial tree
Parent term (use hpo.jax.org/app) Interstitial pulmonary abnormality HP:0006530
Diseases characterized by this term ? (e.g. Orphanet or OMIM number)
Your nano-attribution (ORCID) LMU:chrapp, @kknoflach, @mgriese