Add comment, disease: Milky BAL HP:0033173

[GrieseAG]

HPO term Milky appearance of bronchoalveolar lavage fluid HP:0033173

Suggested revision of textual definition Return of lavage fluid characteristically has a milky apperance in pulmonary alveolar proteinosis (PAP). This is due to the accumulation of a mixture of pulmonary surfactant, which is a lipoprotein complex, in the alveolar space.

PMID: 28771412

Diseases characterized by this term ? (e.g. Orphanet or OMIM number) PAP: ORPHA:747 (Disorder) Autoimmune pulmonary alveolar proteinosis ORPHA:264675 (Disorder) Hereditary pulmonary alveolar proteinosis ORPHA:572428 (Disorder) Infantile-onset pulmonary alveolar proteinosis-hypogammaglobulinemia ORPHA:420259 (Disorder) Secondary pulmonary alveolar proteinosis ORPHA:440427 (Disorder) Severe early-onset pulmonary alveolar proteinosis due to MARS deficiency

Your nano-attribution LMU chrapp; @katrinknoflach, @mgriese

[pnrobinson]

Slight revision

def: Return of lavage fluid with a milky apperance due to the accumulation of a mixture of pulmonary surfactant, which is a lipoprotein complex, in the alveolar space. comment: This feature is characteristically observed in pulmonary alveolar proteinosis.

[pnrobinson]

Diseases

• Surfactant metabolism dysfunction, pulmonary, 4 | 300770
• Surfactant metabolism dysfunction, pulmonary, 5 | 614370
  • Interstitial lung and liver disease | 615486

[pnrobinson]

done