Closed GrieseAG closed 3 years ago
Slight revision
def: Return of lavage fluid with a milky apperance due to the accumulation of a mixture of pulmonary surfactant, which is a lipoprotein complex, in the alveolar space. comment: This feature is characteristically observed in pulmonary alveolar proteinosis.
Diseases
done
HPO term Milky appearance of bronchoalveolar lavage fluid HP:0033173
Suggested revision of textual definition Return of lavage fluid characteristically has a milky apperance in pulmonary alveolar proteinosis (PAP). This is due to the accumulation of a mixture of pulmonary surfactant, which is a lipoprotein complex, in the alveolar space.
PMID: 28771412
Diseases characterized by this term ? (e.g. Orphanet or OMIM number) PAP: ORPHA:747 (Disorder) Autoimmune pulmonary alveolar proteinosis ORPHA:264675 (Disorder) Hereditary pulmonary alveolar proteinosis ORPHA:572428 (Disorder) Infantile-onset pulmonary alveolar proteinosis-hypogammaglobulinemia ORPHA:420259 (Disorder) Secondary pulmonary alveolar proteinosis ORPHA:440427 (Disorder) Severe early-onset pulmonary alveolar proteinosis due to MARS deficiency
Your nano-attribution LMU chrapp; @katrinknoflach, @mgriese