Closed eswietlik closed 3 years ago
@eswietlik could you provide a definition of alveolar volume -- especially, how is it different from other measures of lung volume such as TLC? I have not been able to find a review article on this topic.
@pnrobinson VA term definition and citation now updated
add increased/decreased
@eswietlik adding this comment to provde context Only a portion of each tidal volume (Vt) reaches the alveoli and participates in gas exchange. This is referred to as the alveolar volume (Va). The remainder, the so-called dead space volume (Vd), consists of gas that fills the upper and lower airways (anatomic dead space) or reaches nonperfused or relatively poorly perfused alveoli (alveolar dead space).
Preferred term label: Abnormal alveolar volume (VA)
Synonyms
Definition (free text, please give PubMed ID) Alveolar volume (VA) is a volume accessible during 10-second breath-hold, measured during a single breath manoeuvre. VA is calculated by knowing the fractional concentration of the tracer gas (eg helium) and the volume of the gas inhaled. VA = Vi x(Fi tracer/Fa tracer); Vi - inspired volume of tracer gas, Fi tracer- inspired fraction of tracer gas, Fa tracer - alveolar (exhaled) fraction of tracer gas. PMID 28049168
Parent term (use hpo.jax.org/app) Abnormality in pulmonary function testing HP:0030878
Diseases characterized by this term? (e.g. Orphanet or OMIM number) Pleural mesothelioma ORPHA:50251 Pleural empyema ORPHA:449266 Idiopathic pulmonary fibrosis ORPHA:2032 Congenital lobar emphysema ORPHA:1928 Combined pulmonary fibrosis-emphysema syndrome ORPHA:300564
Your nano-attribution (ORCID) https://orcid.org/0000-0002-4095-8489