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Ontology for the description of human clinical features
http://obophenotype.github.io/human-phenotype-ontology/
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Fetal chylothorax #7220

Closed pnrobinson closed 2 years ago

pnrobinson commented 2 years ago

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pnrobinson commented 2 years ago

https://publications.aap.org/pediatrics/article-abstract/147/3/e2020011601/33244/Congenital-Chylothorax-and-Hydrops-Fetalis-A-Novel?redirectedFrom=fulltext?autologincheck=redirected

pnrobinson commented 2 years ago

Fetal chylothorax

Def: The presence of chyle (a type of lipid-rich lymph) in the pleural space (the space surrounding the lung) as observed in a fetus. PMID:10472400 PMID:28351595

Comment: Fetal chylothorax is associated with a high mortality rate. The most serious consequences of fetal chylothorax are pulmonary hypoplasia, congestive heart failure, and hydrops. It may occur as an isolated disorder or as a feature of diseases such as trisomy 21, Turner syndrome, and Noonan syndrome. Chylous pleural effusion impairs normal development of fetal lungs by pressure effects and can lead to pulmonary hypoplasia, mediastinal shift, and impaired circulation

pnrobinson commented 2 years ago

Structure

Fetal pleural effusion -- fetal hydrothorax -- fetal chylothorax

pnrobinson commented 2 years ago

added