obophenotype / human-phenotype-ontology

Ontology for the description of human clinical features
http://obophenotype.github.io/human-phenotype-ontology/
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Sertoli cell-only phenotype #7578

Closed pnrobinson closed 2 years ago

pnrobinson commented 2 years ago

Preferred term label: Sertoli cell-only phenotype

Synonyms

Definition (free text, please give PubMed ID) A histological phenotype observed on testicular biopsy in which only Sertoli cells line the seminiferous tubules of the testis.

Comment: Sertoli cells are found in the convoluted seminiferous tubules and form part of the blood-testis barrier in males. With Sertoli cell-only phenotype, spermatogenic cells, which are normally located in between the Seroli cells, are absent. PMID:30484998

Parent term (use hpo.jax.org/app)

Diseases characterized by this term ? (e.g. Orphanet or OMIM number) 619831 PMID: 32719396 2/2 also 305700

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pnrobinson commented 2 years ago

added