obophenotype / human-phenotype-ontology

Ontology for the description of human clinical features
http://obophenotype.github.io/human-phenotype-ontology/
Other
294 stars 51 forks source link

NTR: Modifier: radiolucent character to renal stones (Lab: radiology) #8965

Closed pnrobinson closed 3 months ago

pnrobinson commented 1 year ago

New term request Modifier: radiolucent character to renal stones (segal_120706192401): UMLS: 0582428

pnrobinson commented 8 months ago

@MickeySegal

given that current techniques can go much further than just lucency or not, e.g. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443345/, I wonder if this modifier is relevant for modern diagnostics? For instance, "Uric acid stones are typically 200–400 HU, whereas calcium oxalate stones are ~600–1,200 HU". I realize there may be an earlier part of the workup where less is known, but would clinical decisions typically be made on the basis of this (I do not know)

MickeySegal commented 8 months ago

The radiolucent term seems to be in current use: https://www.ncbi.nlm.nih.gov/books/NBK100238/ "Radiolucent kidney stones, detected by ultrasound or computed tomography (CT). Stones are not seen on a plain abdominal x-ray."

pnrobinson commented 3 months ago

I am adding a section called Radiographic modifier

Under this, I added the following

Radiolucent HP:0025789 def: Applies to a lesion that allow x-rays to penetrate through them and expose the receptor (radiolucency). Soft tissues appear black or dark on the processed radiograph and are called radiolucent.